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FEMS Immunology and Medical Microbiology

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Chief Editor: Patrik Bavoil

Thematic Issue coming in February 2010: Neglected Tropical Diseases

edited by M. Capron, V. Mizrahi & P. Timms-

Infectious Diseases: From basic to Translational Research                                                                     The concept of "Neglected Tropical Diseases" is not new, with considerable attention having focused, over the past 10 years, on the "Big Three" diseases, AIDS, malaria and tuberculosis. ... This thematic issue includes asampling of contributions presented at the 1st meeting of the Europe-Africa Frontier Research Conference held in Cape Town... Read more.

Highlight:  Detecttion of antibiotic resistance genes

Extended-spectrum ß-lactamases (ESBLs) are considered to be one of the most important antibiotic resistance mechanisms. This study reported the ESBL-producing genes in 53 randomly selected clinical bacterial isolates from the Steve Biko Academic Hospital. The presence of the blaSHV, blaTEMandblaCTX_M genes was determined, and the overall prevalence of these genes detected in this study was 87% (46/53) in comparision with the literature; theese results wer higher when compared with 33% for Escherichia coli in Denmark for similar pathogens. These research findings indicated that it is crucial to routinely monitor the prevalence of these resistance genes. Read more

  

Vol. 56-3 p.191 (Aug 2009)

Detection of blaSHV, blaTEM and blaCTX-M antibiotic resistance genes in randomly selected bacterial pathogens from the Steve Biko Academic Hospital 
Marthie M. Ehlers, Chrisna Veldsman, Eddy P. Makgotlho, Michael G. Dove, Anwar A. Hoosen, Marleen M. Kock

Scope of the Journal

The editors of FEMS Immunology and Medical Microbiology aim to publish outstanding primary Research Articles and MiniReviews reporting on hypothesis-driven studies relating to infection, infection control and their molecular and cellular correlates. The infection typically involves that of humans or animals by microorganisms of all classes, i.e. viruses, bacteria, fungi or protozoa. The scientific approaches of these studies correspond broadly to the fields of immunology, medical microbiology, cell biology (of infectious diseases), and the biochemistry, molecular biology and genetics of pathogens. These include prominently the overlapping subspecialties of molecular and cellular microbial pathogenesis, host innate and adaptive immune responses to infection, "-omics" of pathogens and/or of the infected host, and modeling of the infection or disease (from biomathematical to in vitro to animal modeling). The Journal will also consider outstanding vaccine-related studies and molecular diagnostic and epidemiology studies that are focused on the infectious agent or the infection process.