FEMS Immunology and Medical MicrobiologyLatest Issue | Online Early | The Publisher | FEMSIM Editorial Board
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Chief Editor: Patrik Bavoil
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From April 2008, the NIH is mandating grant-holders to deposit their published papers in PubMed Central within 12 months of publication. Read more
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| Highlight: Intranasal immunization against Staphylococcus aureus infection |
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The authors investigated whether an intranasal immunization with mutant toxic shock syndrome toxin 1 (TSST-1) could elicit a protective effect against nasal colonization as well as systemic infection of Staphylococcus aureus in a mouse model. Anti-TSST-1 antibody production in the mucosal exudates and in sera was efficiently induced. Bacterial numbers were reduced in spleen, liver and also nasal cavities in the early stage of nasal colonization, and the survival rate was significantly improved in the immunized mice. Read More!
Intranasal immunization of mutant toxic shock syndrome toxin 1 elicits systemic and mucosal immune response against Staphylococcus aureus infection
Kouji Narita, Dong-Liang Hu, Takao Tsuji & Akio Nakane
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Vol. 52-3 p.297 (2008)
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The editors of FEMS Immunology and Medical Microbiology aim to publish outstanding primary Research Articles and MiniReviews reporting on hypothesis-driven studies relating to infection, infection control and their molecular and cellular correlates. The infection typically involves that of humans or animals by microorganisms of all classes, i.e. viruses, bacteria, fungi or protozoa. The scientific approaches of these studies correspond broadly to the fields of immunology, medical microbiology, cell biology (of infectious diseases), and the biochemistry, molecular biology and genetics of pathogens. These include prominently the overlapping subspecialties of molecular and cellular microbial pathogenesis, host innate and adaptive immune responses to infection, "-omics" of pathogens and/or of the infected host, and modeling of the infection or disease (from biomathematical to in vitro to animal modeling). The Journal will also consider outstanding vaccine-related studies and molecular diagnostic and epidemiology studies that are focused on the infectious agent or the infection process.
FEMS IS COMMITTED TO REVIEWING MICROBIOLOGY
Click here for a selection of MiniReviews from this journal!
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