FEMS Immunology and Medical MicrobiologyLatest Issue | Online Early | The Publisher | Editorial Board
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Chief Editor: Patrik Bavoil
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| Thematic Issue: Chlamydia |
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Published in March 2009...
Guest Editors:
G. Christiansen & S.Birkelund
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FEMS is committed to reviewing Microbiology
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click here for a free selection of MiniReviews
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Highlight: TLR2, TLR4 and Aspergillus fumigatus infection
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Toll-like receptors (TLRs) are key components of the innate immune system that detects microbial infection and triggers host defensive responses. To determine the roles of TLR2 and TLR4 in corneal epithelial cells in mediating innate responses against Aspergillus fumigatus, telomerase-immortalized human corneal epithelial cells (THCE) were challenged by TLR2 ligand zymosan, TLR4 ligand lipopolysaccharide and A. fumigatus hyphae, respectively. Our results suggested that Corneal epithelial cells play a role in innate defense against fungal infection through the mediation of inflammatory cytokines production...Read more!
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Vol. 56-1 p.88 (June 2009)
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Innate responses of corneal epithelial cells against Aspergillus fumigatus challenge
Hui Guo & Xinyi Wu
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The editors of FEMS Immunology and Medical Microbiology aim to publish outstanding primary Research Articles and MiniReviews reporting on hypothesis-driven studies relating to infection, infection control and their molecular and cellular correlates. The infection typically involves that of humans or animals by microorganisms of all classes, i.e. viruses, bacteria, fungi or protozoa. The scientific approaches of these studies correspond broadly to the fields of immunology, medical microbiology, cell biology (of infectious diseases), and the biochemistry, molecular biology and genetics of pathogens. These include prominently the overlapping subspecialties of molecular and cellular microbial pathogenesis, host innate and adaptive immune responses to infection, "-omics" of pathogens and/or of the infected host, and modeling of the infection or disease (from biomathematical to in vitro to animal modeling). The Journal will also consider outstanding vaccine-related studies and molecular diagnostic and epidemiology studies that are focused on the infectious agent or the infection process.
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